
Reply To: Caseous Lymphadenitis (CL)
Article discusses vaccine advances, cellular activity of the bacteria, and sensitivity to antibiotics.
Excerpt:
Bacteria not controlled by the abscess wall enter the capillaries and form colonies that occlude the blood vessels, generating ischemia that, together with toxins, destroy the cells of healthy tissue, increasing the necrotic mass. Viable bacteria spread through the lymphatic vessels and penetrate other lymph nodes and blood vessels, reaching different organs where abscess formation is repeated. This behavior originates the clinical manifestations of the visceral type of the disease, which affects internal lymph nodes and organs, especially lungs and liver.