
Reply To: Nutritional Yeast
Then, if we go look up cyanocobalamin on NIH, we get some concerning news:
Adverse Effects
Though only a vitamin, cyanocobalamin can cause several adverse drug reactions, including allergic reactions like itching, erythema, and wheals.[25] Cyanocobalamin therapy’s cutaneous adverse drug reactions include acne, rosacea, and anaphylaxis with cyanocobalamin injections. Cobalt is a component of cobalamin; consequently, patients with cobalt sensitivity have been reported to have allergic manifestations when receiving cobalamin replacement therapy.[26]
Other common adverse effects include:
Shortness of breath (even with mild exertion), swelling, rapid weight gain
Pulmonary edema, congestive heart failure; peripheral vascular thrombosis
Hypokalemia–leg cramps, irregular heartbeats, tingling/numbness, muscle weakness, or limp feeling
Numbness or tingling and joint pain
Fever
Swollen tongue
Itching or rash
Polycythemia; cyanocobalamin can unmask the underlying polycythemia. Patients with myeloproliferative disorders like polycythemia vera have an increased prevalence of vitamin B12 deficiency, despite high serum vitamin B12 levels.