Reply To: Magnesium

  • theholisticgoat

    March 9, 2024 at 7:57 pm


    The bioavailability of magnesium in chlorophyll is a topic of interest due to the essential role of magnesium in human health and its central position in the chlorophyll molecule, which is abundant in green plants.

    Key Insights from Research Papers

    • Chlorophyll-a and chlorophyll-b are in isotopic equilibrium, suggesting that magnesium is labile within these molecules during the chlorophyll cycle after biosynthesis, which may have implications for its bioavailability1.
    • A slight depletion of heavier magnesium isotopes in chlorophyll-a relative to the culture medium was observed, indicating a mass-dependent fractionation possibly due to chelation during intracellular processes, such as those mediated by the magnesium-chelatase enzyme2.
    • In commonly consumed vegetables and fruits, chlorophyll-bound magnesium represents a very low fraction of total magnesium intake, less than 1% in industrialized countries, suggesting that its contribution to magnesium nutrition is minimal4.


    The research indicates that magnesium within chlorophyll molecules is labile and may undergo isotopic fractionation during biosynthesis and intracellular processes. However, despite the central role of magnesium in chlorophyll, its contribution to overall magnesium nutrition from dietary sources appears to be very low, with chlorophyll-bound magnesium constituting a minor fraction of total magnesium intake.